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KMID : 1143420160090200369
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Public Health Weekly Report
2016 Volume.9 No. 20 p.369 ~ p.372
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Laboratory Tests of Human Granulocytic Anaplasmosis, 2015
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Lee Seung-Hun
Hwang Seon-Do
Lee Yeong-Seon
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Abstract
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This article discusses the results of the laboratory tests of Human Granulocytic Anaplasmosis (HGA) from a suspected patient in South Korea. HGA is a zoonotic tick-borne disease and the agent is known as Anaplasma phagocytophilum which is mainly transmitted by ticks. We performed serological tests of HGA using indirect immuno-fluorescent antibody assay (IFA) from the serum of a total of 201 patients. Also, we performed the PCR test using 16S rRNA target gene from 118 cases of the patients’ blood. In serological tests using IFA, IgG or IgM for A. phagocytohilum were found in 14 of the 201 cases; 4 of the 9 cases which had convalescent sera showed seroconversion. Three of the 118 cases showed positive results during the PCR test. This article provides a basis for the laboratory diagnosis of febrile patients who had fever with a recent history of tick bites during their outdoor activity.
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